Aplastic anemia is a disorder of the bone marrow, where the bone marrow\u2019s stem cells are damaged and do not make enough blood cells. There are three types of blood cells each with a very specific role. Red blood cells transport oxygen around the body and take carbon dioxide to the lungs, white blood cells form part of the immune system and help the body fight infections, while platelets stick together to stop bleeding from cuts.[1]<\/sup><\/p>\n There are a variety of health problems that can occur as a result of aplastic anemia including; bleeding, infections, heart failure, irregular heart beats, and even death.[1]<\/sup><\/p>\n There are several types of aplastic anemia; it can be inherited, in forms such as Fanconi anemia or Diamond-Blackfan anemia, or it can be acquired. There are several causes of acquired aplastic anemia including infection, exposure to certain viruses, exposure to certain toxins, drugs, and more.[2]<\/sup><\/p>\n A stem cell transplant is the only real cure for aplastic anemia, with allogeneic stem cell transplants being the preferred method. Allogeneic stem cells come from a donor, who could be a sibling, another family member, or a stranger found on a stem cell registry.[3]<\/sup><\/p>\n A Phase 1 clinical trial is aiming to determine the efficacy and toxicity of using a patient\u2019s own stem cells to treat the hereditary form of Fanconi anemia. The stem cells have been modified in the laboratory to correct the defective gene which causes FA.[7]<\/sup><\/p>\n The information contained in this article is for information purposes only and is not intended to replace the advice of a medical expert. If you have any concerns about your health we urge you to discuss them with your doctor.<\/em><\/p>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_video src=”https:\/\/youtu.be\/F-bch1U7pTE” _builder_version=”4.16″ global_colors_info=”{}”][\/et_pb_video][et_pb_text _builder_version=”4.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” use_border_color=”off” border_color=”#ffffff” border_style=”solid” global_colors_info=”{}”]\n Titus Chang has severe congenital Aplastic Anemia. Titus received a stem cell transplant using stem cells from umbilical cord blood; 98% of the stem cells in the cord blood were viable after thawing. The transplant means that Titus can return to a normal life.<\/em><\/span><\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|desktop” module_class=”down-arrow” _builder_version=”4.27.4″ background_color=”#bd144f” custom_padding=”0px||0px|” custom_padding_tablet=”50px|0|50px|0″ custom_padding_phone=”” transparent_background=”off” padding_mobile=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on” locked=”off” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_toggle title=”GET YOUR FREE INFO KIT” icon_color=”RGBA(255,255,255,0)” open_icon_color=”RGBA(255,255,255,0)” icon_color_tablet=”RGBA(255,255,255,0)” icon_color_phone=”RGBA(255,255,255,0)” icon_color_last_edited=”off|phone” open_icon_color_tablet=”RGBA(255,255,255,0)” open_icon_color_phone=”RGBA(255,255,255,0)” open_icon_color_last_edited=”on|phone” disabled_on=”off|off|off” _builder_version=”4.27.4″ _module_preset=”default” custom_css_free_form=”selector {|| padding: 0;|| background: none;|| border: 0;||}||selector h5 {|| text-align: center;|| padding: 10px 20px!important;|| font-size: 28px;|| color: #bd144f!important;\t|| background: #fff;|| border-radius: 60px;|| text-wrap: balance;|| width: fit-content;|| margin-bottom: 1.5em;|| margin-left: auto;|| margin-right: auto;||}||selector div.et_pb_toggle_content {|| padding: 1.5em;|| background: #fff;|| margin-bottom: 2em;||}” icon_color__hover=”RGBA(255,255,255,0)” icon_color__hover_enabled=”off|desktop” locked=”off” global_colors_info=”{}” open_icon_color__hover_enabled=”on|desktop” open_icon_color__hover=”RGBA(255,255,255,0)”]\n\n <\/p> Aplastic Anemia Facts<\/h3>\n
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Aplastic Anemia and Stem Cells<\/h3>\n
References<\/h3>\n
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