{"id":1290,"date":"2015-02-09T10:06:25","date_gmt":"2015-02-09T10:06:25","guid":{"rendered":""},"modified":"2016-05-10T08:40:30","modified_gmt":"2016-05-10T08:40:30","slug":"congenital-heart-disease","status":"publish","type":"post","link":"https:\/\/cells4life.com\/us\/2015\/02\/congenital-heart-disease\/","title":{"rendered":"Congenital Heart Disease"},"content":{"rendered":"<div class=\"body\">\n<div>\n<p>We\u2019re continuing our support of National Heart Awareness Month as we look at congenital heart disease throughout this week and how stem cells could offer CHD patients hope.<\/p>\n<p>Congenital heart disease is general term for a range of birth defects which affect the way the heart works. \u00a0Congenital heart disease affects approximately 9 in every 1,000 babies born in the UK making it one of the most common types of birth defect <sup>[1]<\/sup>.<\/p>\n<p>Generally the causes of congenital heart are unknown but there are certain things known to increase the risk including:<\/p>\n<p>\u2022 <a href=\"https:\/\/cells4life.com\/2014\/03\/downs-syndrome-awareness-week\/\">Down\u2019s Syndrome<\/a> and other genetic conditions<\/p>\n<p>\u2022 Rubella and certain other infections during pregnancy<\/p>\n<p>\u2022 <a href=\"https:\/\/cells4life.com\/type-1-diabetes-and-stem-cells\/\">Diabetes<\/a>; poor management of type 1 and type 2 diabetes in pregnancy<\/p>\n<p>\u2022 Alcohol abuse during pregnancy<\/p>\n<p>\u2022 Taking certain medications in pregnancy, including ibuprofen <sup>[2]<\/sup><\/p>\n<p>Down\u2019s syndrome is the most common cause of congenital heart defects however there are steps women can take before and during pregnancy to minimise the risk of their baby developing a congenital heart defect. \u00a0These can include making sure their immunisations are up to date, avoiding alcohol, managing diabetes effectively and avoiding certain medications.<\/p>\n<p>Congenital heart defects can be diagnosed during pregnancy so armed with the information that the diagnosis brings, parents can plan in advance and make the choice to bank their child\u2019s cord blood to give them access to stem cell therapies and clinical trials. \u00a0Congenital heart defects can range from a small hole in the heart which may heal itself with time or be as severe as half of the heart not being there at all.<\/p>\n<p>Congenital heart disease refers to a range of congenital heart defects; each defect affects the heart differently:<\/p>\n<p><a href=\"http:\/\/www.patient.co.uk\/health\/aortic-stenosis-leaflet\" target=\"_blank\" rel=\"noopener\">Aortic valve stenosis<\/a><\/p>\n<p><a href=\"http:\/\/www.patient.co.uk\/doctor\/coarctation-of-the-aorta-pro\" target=\"_blank\" rel=\"noopener\">Coarctation of the aorta\u00a0<\/a><\/p>\n<p><a href=\"http:\/\/www.patient.co.uk\/doctor\/ebsteins-anomaly\" target=\"_blank\" rel=\"noopener\">Ebstein&#8217;s anomaly\u00a0<\/a><\/p>\n<p><a href=\"http:\/\/www.nhlbi.nih.gov\/health\/health-topics\/topics\/pda\" target=\"_blank\" rel=\"noopener\">Patent ductus arteriosus<\/a><\/p>\n<p><a href=\"http:\/\/www.mayoclinic.org\/diseases-conditions\/pulmonary-valve-stenosis\/basics\/definition\/con-20013659\" target=\"_blank\" rel=\"noopener\">Pulmonary valve stenosis<\/a><\/p>\n<p><a href=\"http:\/\/www.mayoclinic.org\/diseases-conditions\/ventricular-septal-defect\/basics\/definition\/con-20024118\" target=\"_blank\" rel=\"noopener\">Septal defects\u00a0<\/a><\/p>\n<p><a href=\"http:\/\/www.gosh.nhs.uk\/medical-information\/search-for-medical-conditions\/tetralogy-of-fallot\/\" target=\"_blank\" rel=\"noopener\">Tetralogy of Fallot<\/a><\/p>\n<p><a href=\"http:\/\/www.heart.org\/HEARTORG\/Conditions\/CongenitalHeartDefects\/AboutCongenitalHeartDefects\/Total-Anomalous-Pulmonary-Venous-Connection-TAPVC_UCM_307039_Article.jsp\" target=\"_blank\" rel=\"noopener\">Total anomalous pulmonary venous connection<\/a><\/p>\n<p><a href=\"http:\/\/www.mayoclinic.org\/diseases-conditions\/transposition-of-the-great-arteries\/basics\/definition\/con-20043232\" target=\"_blank\" rel=\"noopener\">Transposition of the great arteries<\/a><\/p>\n<p><a href=\"http:\/\/www.cdc.gov\/ncbddd\/heartdefects\/truncusarteriosus.html\" target=\"_blank\" rel=\"noopener\">Truncus arteriosus<\/a> <sup>[1]<\/sup><\/p>\n<p>The symptoms of congenital heart defects can vary, however, the general symptoms to look out for are:<\/p>\n<p>\u2022 excessive sweating<\/p>\n<p>\u2022 extreme tiredness and fatigue<\/p>\n<p>\u2022 poor feeding<\/p>\n<p>\u2022 rapid heartbeat<\/p>\n<p>\u2022 rapid breathing<\/p>\n<p>\u2022 shortness of breath<\/p>\n<p>\u2022 chest pain<\/p>\n<p>\u2022 a blue tinge to the skin (cyanosis)<\/p>\n<p>\u2022 clubbed fingernails <sup>[3]<\/sup><\/p>\n<p>It is important to seek medical advice immediately if you think someone you know may have a congenital heart defect.<\/p>\n<p>Stem cells are being used in a range of ways to try and find effective treatments for congenital heart defects including tissue engineered replacement valves to the use of cord blood to try and strengthen heart muscle of those born with hypoplastic left heart syndrome. \u00a0Over the course of the week we will look at stem cells and congenital heart disease in more detail.<\/p>\n<p>If you have other concerns about congenital heart disease or would like more information, please consult your GP or midwife.<\/p>\n<p style=\"box-sizing: border-box; margin: 0px 0px 10px;\"><span style=\"color: #6d6e71; font-family: 'Open Sans', sans-serif;\"><span style=\"font-size: 14px; line-height: 20px;\"><sup>[1]<\/sup>\u00a0<a href=\"http:\/\/www.nhs.uk\/Conditions\/Congenital-heart-disease\/Pages\/Introduction.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/www.nhs.uk\/Conditions\/Congenital-heart-disease\/Pages\/Introduction.aspx<\/a><\/span><\/span><\/p>\n<p style=\"box-sizing: border-box; margin: 0px 0px 10px;\"><span style=\"color: #6d6e71; font-family: 'Open Sans', sans-serif;\"><span style=\"font-size: 14px; line-height: 20px;\"><sup>[2]<\/sup> <a href=\"http:\/\/www.nhs.uk\/Conditions\/Congenital-heart-disease\/Pages\/Causes.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/www.nhs.uk\/Conditions\/Congenital-heart-disease\/Pages\/Causes.aspx<\/a><\/span><\/span><\/p>\n<p style=\"box-sizing: border-box; margin: 0px 0px 10px;\"><span style=\"color: #6d6e71; font-family: 'Open Sans', sans-serif;\"><span style=\"font-size: 14px; line-height: 20px;\"><sup>[3]<\/sup> <a href=\"http:\/\/www.nhs.uk\/Conditions\/Congenital-heart-disease\/Pages\/Symptoms.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/www.nhs.uk\/Conditions\/Congenital-heart-disease\/Pages\/Symptoms.aspx<\/a><\/span><\/span><\/p>\n<\/div>\n<\/div>\n<div class=\"field_image_miniblog\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>We\u2019re continuing our support of National Heart Awareness Month as we look at congenital heart disease throughout this week and how stem cells could offer CHD patients hope. Congenital heart disease is general term for a range of birth defects which affect the way the heart works. \u00a0Congenital heart disease affects approximately 9 in every [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3061,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[55],"tags":[],"class_list":["post-1290","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"_links":{"self":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/1290","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/comments?post=1290"}],"version-history":[{"count":0,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/1290\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/media\/3061"}],"wp:attachment":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/media?parent=1290"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/categories?post=1290"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/tags?post=1290"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}