{"id":27565,"date":"2022-06-21T13:24:01","date_gmt":"2022-06-21T13:24:01","guid":{"rendered":"https:\/\/cells4life.com\/?p=27565"},"modified":"2024-05-29T14:34:51","modified_gmt":"2024-05-29T14:34:51","slug":"car-t-cell-therapy","status":"publish","type":"post","link":"https:\/\/cells4life.com\/us\/2022\/06\/car-t-cell-therapy\/","title":{"rendered":"CAR T Cell Therapy"},"content":{"rendered":"[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Header text&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;Text: (Is this the beginning of the end&#8230;)&#8221; _builder_version=&#8221;4.19.1&#8243; background_enable_color=&#8221;off&#8221; custom_padding=&#8221;10px|0px|5px|0px|false|false&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]\n<p>Is This The Beginning of the End\u2026for Cancer?<\/p>\n<p><em>Well, it could be. A positive story for our times. Read all about how specialist immunotherapy treatment saved a little girl\u2019s life. And how 10 years on, she\u2019s still cancer-free and looking forward to a great future.<\/em><\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=&#8221;Section 1 &#8211; Before Story &#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Text: (Everyone loves a&#8230;)&#8221; _builder_version=&#8221;4.19.1&#8243; background_enable_color=&#8221;off&#8221; custom_padding=&#8221;0px|0px|5px|0px|false|false&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]\n<p>Everyone loves a story with a happy ending. Here at Cells4Life, we\u2019re no exception. Especially when it concerns such positive, close parallels to our family cord blood banking service.<\/p>\n<p>It goes without saying that with any life-threatening condition \u2013 cancer being one of the deadliest &#8211; there\u2019s always going to be a note of caution. A caveat, perhaps. None of us can predict the future, after all. With this in mind, we\u2019re delighted to bring you this wonderful, true story. And to rejoice in the near-miracle medical breakthrough that has offered someone another chance when everything seemed lost.<\/p>\n<p>In addition, we\u2019ll explore how, were you to save your baby\u2019s stem cells immediately after birth, he or she could also benefit from the powerful therapies offered by stem cell technology.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=&#8221;Section 2 &#8211; (Meet Emily)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Title: Meet Emily&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<h3><strong>Meet Emily<\/strong><\/h3>\n[\/et_pb_text][et_pb_text admin_label=&#8221;Text: (Emily whitehead is now 17&#8230;)&#8221; _builder_version=&#8221;4.19.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<p><a href=\"https:\/\/www.today.com\/video\/first-child-to-receive-car-t-cell-therapy-is-10-years-cancer-free-139772997670?search=emily%20whitehead\" target=\"_blank\" rel=\"noopener\">Emily Whitehead<\/a> is now 17, a young woman in America with many exciting years in front of her. On the brink of adulthood, she has a bright future. CAR T-cell therapy saved her life. But, for a while, her prognosis was dark.<\/p>\n<p>When she was just five years old, she was diagnosed with acute lymphoblastic leukaemia.This is a type of cancer that affects white blood cells and it progressed quickly, and aggressively. Having experienced gruelling chemotherapy, and rapidly declining health, two years later her parents learned that sadly, she was highly unlikely to survive.<\/p>\n<p>(For information, lymphoma differs from leukaemia: the former affects mainly the lymph nodes, while the latter is concerned with blood and bone marrow.)<\/p>\n<p><a href=\"https:\/\/www.nhs.uk\/conditions\/acute-lymphoblastic-leukaemia\/#:~:text=Acute%20lymphoblastic%20leukaemia%20is%20a,each%20year%20in%20the%20UK\" target=\"_blank\" rel=\"noopener\">Lymphoblastic leukaemia<\/a> is rare; in the UK, for example, only around 790 people are diagnosed with the condition each year, with most cases developing in children, teenagers and young adults.<\/p>\n<p>Emily\u2019s parents\u2019 grit and determination to save their little girl empowered them to consider a new immunotherapy treatment \u2013 a clinical trial designed to transform her immune system into its own powerful weapon against cancer. Emily was Patient 1, the first child ever enrolled in this process.<\/p>\n<p>Was it guaranteed? No. Would it work? Read on to find out more.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=&#8221;Section 3 &#8211; (Welcome to:)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Title: CAR T-Cell Therapy&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<h3><strong>CAR T-Cell Therapy<\/strong><\/h3>\n[\/et_pb_text][et_pb_text admin_label=&#8221;Text: (CAR stands for&#8230;)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<p>CAR stands for Chimeric Antigen Receptor.<\/p>\n<p>But first, let us explain what T-cells do.<\/p>\n<p>Imagine T-cells as our knights in shining armour, moving around the body finding and destroying harmful or defective cells. Were we to come into contact with a new disease or infection, our T cells step up to fight them. And they\u2019re excellent defenders.<\/p>\n<p>Except when it comes to cancer cells, which can easily be missed because the T cells can\u2019t always tell the difference between these, and a normal cell. So, this situation needs to be remedied, which is where CAR T-Cell Therapy comes into play.<\/p>\n<p>CAR T-Cell Therapy takes a sample of T-cells from the blood \u2013 this is called apheresis. In the lab, they change the T-cells \u2013 in other words, they use a form of genetic engineering. These new cells can then recognise and target a specific protein on the cancer cells.<\/p>\n<p>They multiply in the lab, and then, when there\u2019s enough of them to have an influence, scientists put them back into the bloodstream, enabling the T-cells to fight cancerous cells as effectively as they battle against other conditions and infections.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=&#8221;Section 4 (Back to Emily)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Title:  (Back to Emily)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<h3><strong>Back to Emily<\/strong><\/h3>\n[\/et_pb_text][et_pb_text admin_label=&#8221;Text: (and THIS is&#8230;)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<p>And THIS, is what happened with Emily Whitehead. Her parents referred to this process as sending the T-Cells to \u201cbootcamp\u201d, which we think sums everything up perfectly.<\/p>\n<p>After developing a high fever, which was expected, she was put on a ventilator and watched carefully. Emily woke up on her seventh birthday, and eight days later the doctors declared her cancer-free.<\/p>\n<p>She has remained so ever since.<\/p>\n<p>As of August 2021, there are now five US Federal Drug Administration CAR T-Cell Therapies for people with cancer, due in no small part to the bravery of a small girl, and the foresight and courage of her parents.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=&#8221;Section 7 (How Does Stem Cell Storage Work?)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Title: (How Does Stem Cell Storage Work?)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<h3><strong>How Does Stem Cell Storage Work?<\/strong><\/h3>\n[\/et_pb_text][et_pb_text admin_label=&#8221;Text: (Given that medical break&#8230;)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<p>Given that medical breakthroughs are happening all the time, it makes sense to harvest and store the stem cells found in your new born baby\u2019s placenta and umbilical cord. Why? Because here, and just at this time there is an ultra-rich supply of these special cells. (They deplete as we grow up.)<\/p>\n<p>The potency of stem cells comes from their ability to become any cell in the human body \u2013 nerves, blood, muscles, and so on. Thus, they have properties that scientists can use to treat the root cause of many, many health issues.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=&#8221;Section 8 (Is Stem Cell Banking Worth It?)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Title: (Is Stem Cell Banking Worth It?)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<h3><strong>Is Stem Cell Banking Worth It?<\/strong><\/h3>\n[\/et_pb_text][et_pb_text admin_label=&#8221;Text: (An unambiguous&#8230;)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<p>An unambiguous \u201cyes\u201d from us here at Cells4Life.<\/p>\n<p>Truly, health is wealth. With stem cell technology, wellbeing into his or her middle and old age could offer your child the greatest of legacies.<\/p>\n<p>Whilst the years yet to come are unknown, stem cells are almost certainly the future of medicine. Many exciting new developments are more than possible using these types of cells, not least in their incredible means to repair or replace human cells, tissues or organs, restoring them to a completely normal function.<\/p>\n<p>Including lymphoblastic leukaemia, now hopefully well in Emily\u2019s past.<\/p>\n<p><em>Why not download a Welcome Pack? It\u2019s full of useful, jargon-free information all about stem cell banking. Just enter your details below.<\/em><\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=&#8221;RWP Blog&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;RWP&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#bd114f&#8221; background_layout=&#8221;dark&#8221; custom_padding=&#8221;20px|20px|20px|20px&#8221; global_colors_info=&#8221;{}&#8221;]\n<h2 style=\"text-align: center;\">Request a Welcome Pack<\/h2>\n<p style=\"text-align: center;\">Find out more about cord blood banking by downloading a Welcome Pack now.<\/p>\n\n<div class=\"wpcf7 no-js\" id=\"wpcf7-f14118-o1\" lang=\"en-US\" dir=\"ltr\" data-wpcf7-id=\"14118\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/us\/wp-json\/wp\/v2\/posts\/27565#wpcf7-f14118-o1\" method=\"post\" class=\"wpcf7-form init\" aria-label=\"Contact form\" novalidate=\"novalidate\" data-status=\"init\">\n<fieldset class=\"hidden-fields-container\"><input type=\"hidden\" name=\"_wpcf7\" value=\"14118\" \/><input type=\"hidden\" name=\"_wpcf7_version\" value=\"6.1.5\" \/><input type=\"hidden\" name=\"_wpcf7_locale\" value=\"en_US\" \/><input type=\"hidden\" name=\"_wpcf7_unit_tag\" value=\"wpcf7-f14118-o1\" \/><input type=\"hidden\" name=\"_wpcf7_container_post\" value=\"0\" \/><input type=\"hidden\" name=\"_wpcf7_posted_data_hash\" value=\"\" \/>\n<\/fieldset>\n<p>Title* <span class=\"wpcf7-form-control-wrap\" data-name=\"salutation\"><select class=\"wpcf7-form-control wpcf7-select wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" name=\"salutation\"><option value=\"- Select -\">- Select -<\/option><option 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name=\"assigned_user_id\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"e4987368-af56-291e-0908-4e82dbf541c4\" type=\"hidden\" name=\"created_by\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"rwp\" type=\"hidden\" name=\"lead_source\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"{EXT_REFERER}\" type=\"hidden\" name=\"webform_referrer_url_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"{COOKIE:_#uid}\" type=\"hidden\" name=\"webform_contact_id_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"request-welcome-pack\" type=\"hidden\" name=\"originating_web_form_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"{IP_ADDRESS}\" type=\"hidden\" name=\"webform_ip_address_c\" \/><input type='hidden' class='wpcf7-pum' value='{\"closepopup\":false,\"closedelay\":0,\"openpopup\":false,\"openpopup_id\":0}' \/><div class=\"wpcf7-response-output\" aria-hidden=\"true\"><\/div>\n<\/form>\n<\/div>\n\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Reference&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Text:  reference &#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]\n<p>If someone you love is affected by cancer or more specifically leukaemia, you&#8217;ll want to support them as best you can. If you would like to know more about this disease check out the great work the charity <strong>Young Lives vs Cancer<\/strong> are doing <a href=\"http:\/\/www.younglivesvscancer.org.uk\/\" target=\"_blank\" rel=\"noopener\">here<\/a>.<\/p>\n<p>There are also plenty of resources to be found on the<strong> Cancer Research UK<\/strong> site <a href=\"https:\/\/www.cancerresearchuk.org\/\" target=\"_blank\" rel=\"noopener\">here<\/a> where you can learn more and help fund further research into cancer.<\/p>\n<p>None of the information on this website pertains to medical advice. For medical advice and support with your healthcare please speak to your designated Healthcare provider.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"<p>Is This The Beginning of the End\u2026for Cancer? Well, it could be. A positive story for our times. Read all about how specialist immunotherapy treatment saved a little girl\u2019s life. And how 10 years on, she\u2019s still cancer-free and looking forward to a great future.Everyone loves a story with a happy ending. Here at Cells4Life, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":27583,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[55,87,75],"tags":[],"class_list":["post-27565","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","category-stem-cell-news","category-uses-for-cord-blood"],"_links":{"self":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/27565","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/comments?post=27565"}],"version-history":[{"count":29,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/27565\/revisions"}],"predecessor-version":[{"id":32674,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/27565\/revisions\/32674"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/media\/27583"}],"wp:attachment":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/media?parent=27565"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/categories?post=27565"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/tags?post=27565"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}