{"id":29250,"date":"2023-03-03T19:00:08","date_gmt":"2023-03-03T19:00:08","guid":{"rendered":"https:\/\/cells4life.com\/?p=29250"},"modified":"2023-03-23T15:41:49","modified_gmt":"2023-03-23T15:41:49","slug":"fifth-person-cure-hiv-using-stem-cells","status":"publish","type":"post","link":"https:\/\/cells4life.com\/us\/2023\/03\/fifth-person-cure-hiv-using-stem-cells\/","title":{"rendered":"D\u00fcsseldorf Patient becomes fifth person cured of HIV using stem cells"},"content":{"rendered":"[et_pb_section fb_built=”1″ admin_label=”Content” _builder_version=”4.19.1″ _module_preset=”default” collapsed=”off” global_colors_info=”{}”][et_pb_row _builder_version=”4.17.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.17.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_text admin_label=”Blog content” _builder_version=”4.19.1″ _module_preset=”default” global_colors_info=”{}”]\n

You may remember a previous blog from less than a year ago discussing four individuals who were\u00a0cured of their HIV<\/a>\u00a0after receiving stem cell transplants. Well, the amazing news keeps coming as a 53-year-old leukaemia patient from D\u00fcsseldorf has just become the fifth.<\/p>\n

Read on for the whole story.<\/p>\n

Stem cells and leukaemia<\/h2>\n

Before we jump right in, it is worth mentioning that stem cell treatments are currently used as one treatment for leukaemia.<\/p>\n

Leukaemia is a type of blood cancer that affects the bone marrow and then the blood cells. It starts in the marrow but can then enter the bloodstream and subsequently affect the other cells and organs in a body.<\/p>\n

With a transplant, the procedure replaces damaged cells. According to the\u00a0Siteman Cancer Centre<\/a>, transplanting stem cells, usually from bone marrow, replenishes the blood stem cells in the patient\u2019s bone marrow so they can begin to produce healthy new blood cells.<\/p>\n

The transplant is often used in conjunction with radiation or chemotherapy and can result in long-lasting remission and even a cure.<\/p>\n

Bone marrow donations are one way this procedure can be done. There are also peripheral blood donations and cord blood donations. Donations are usually found via the NHS cord blood bank.<\/p>\n

The doctor can use the\u00a0cells<\/a>\u00a0from the patient\u2019s own body too.<\/p>\n

The D\u00fcsseldorf Patient<\/h2>\n

A 53-year-old man, known as\u00a0The D\u00fcsseldorf Patient<\/a>, was diagnosed with HIV in 2008. He received antiretroviral therapy (ART) to suppress the viral load within his immune system, before enrolling in the University Hospital D\u00fcsseldorf IciStem program<\/a> which explores stem cell treatment as a way of curing HIV.<\/p>\n

Three years later the patient received a diagnosis of acute myeloid leukaemia. He did achieve remission through an initial round of chemotherapy but shortly thereafter relapsed.<\/p>\n

Two years after the leukaemia diagnosis he received a stem cell transplant from a donor. This donor had a mutation that is believed to be resistant to HIV infection.<\/p>\n

When 2018 came around, after continuing the ART and post-stem cell treatment, the patient was tested, and they were unable to find any trace of the HIV. Ten years after the initial HIV diagnosis, the patient appears to be cured.<\/p>\n

The patient\u2019s physician,\u00a0Bj\u00f6rn-Erik Ole Jensen<\/a>, came forward with these findings in 2019, but believed it was too early to say if his patient was in remission, however he expressed optimism. Now, in 2023, he is happy to conclude that the treatment was a success.<\/p>\n

Things look promising<\/h2>\n

Interestingly, the first patient believed to be cured of HIV, Timothy Brown, received the same type of transplant as this Dusseldorf Patient back in 2007. It was also reported in 2022 that a woman was cured of HIV<\/a> using umbilical cord blood stem cells.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.17.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.17.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_testimonial author=”Professor Jurgen Rockstroh” _builder_version=”4.19.1″ _module_preset=”default” global_colors_info=”{}”]\n

 <\/p>\n

\u201cThis underlines that these approaches are promising and also reproducible, since it does not remain an isolated case.\u201d<\/em><\/p>\n

– Professor Jurgen Rockstroh, Head of Infectiology, University Hospital Bonn<\/p>\n

 <\/p>\n[\/et_pb_testimonial][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.17.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.19.1″ _module_preset=”default” global_colors_info=”{}”]\n

That makes three people who have benefitted from stem cell transplants. The other two cases from the five people are believed to have been cured when their own immune system eliminated the virus by itself, without treatment, something scientists have so far been unable to explain.<\/p>\n

HIV is a virus many people will have heard of and thankfully the conversation surrounding it has now moved on to talk of a possible cure. Further research will need to be conducted to test the chances of this being a treatment. However, three people have now been \u2018cured\u2019 of their HIV using stem cells, so thing looks promising.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”RWP” _builder_version=”4.19.1″ _module_preset=”default” collapsed=”off” global_colors_info=”{}”][et_pb_row admin_label=”RWP Blog” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.19.1″ background_color=”#bd114f” background_layout=”dark” custom_padding=”20px|20px|20px|20px” global_colors_info=”{}”]\n

Request a Welcome Pack<\/h2>\n

Find out more about cord blood banking by downloading a Welcome Pack now.<\/p>\n\n

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    You may remember a previous blog from less than a year ago discussing four individuals who were\u00a0cured of their HIV\u00a0after receiving stem cell transplants. Well, the amazing news keeps coming as a 53-year-old leukaemia patient from D\u00fcsseldorf has just become the fifth. Read on for the whole story. Stem cells and leukaemia Before we jump […]<\/p>\n","protected":false},"author":1,"featured_media":29260,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[55,60,1],"tags":[],"class_list":["post-29250","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","category-news","category-other"],"_links":{"self":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/29250","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/comments?post=29250"}],"version-history":[{"count":7,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/29250\/revisions"}],"predecessor-version":[{"id":29419,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/29250\/revisions\/29419"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/media\/29260"}],"wp:attachment":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/media?parent=29250"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/categories?post=29250"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/tags?post=29250"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}