{"id":31738,"date":"2024-01-24T09:30:44","date_gmt":"2024-01-24T09:30:44","guid":{"rendered":"https:\/\/cells4life.com\/?p=31738"},"modified":"2025-11-25T15:39:49","modified_gmt":"2025-11-25T15:39:49","slug":"stem-cells-go-to-space","status":"publish","type":"post","link":"https:\/\/cells4life.com\/us\/2024\/01\/stem-cells-go-to-space\/","title":{"rendered":"Stem Cells Go to Space"},"content":{"rendered":"[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]\n<p class=\"ai-optimize-58\"><span style=\"font-weight: 400;\">This month sees two important missions lifting-off into space, both of which will carry out pioneering stem cell research.<\/span><\/p>\n<p class=\"ai-optimize-59\"><span style=\"font-weight: 400;\">The first of these has already launched. On 18 January, Ax-3, the third mission by private company Axiom to be launched using Space X rockets, departed for the International Space Station. <a href=\"https:\/\/www.axiomspace.com\/missions\/ax3#research\" target=\"_blank\" rel=\"noopener\">[1]<\/a><\/span><\/p>\n<p class=\"ai-optimize-60\"><span style=\"font-weight: 400;\">Aboard were four astronauts who over the course of two weeks will carry out a variety of experiments in microgravity.<\/span><\/p>\n<p class=\"ai-optimize-61\"><span style=\"font-weight: 400;\">Amongst them will be several significant ones relating to stem cells.<\/span><\/p>\n<p class=\"ai-optimize-62\"><span style=\"font-weight: 400;\">The Sanford Stem Cell Institute (SSCI) operating out of the University of California, San Diego will be paying close attention to the astronauts\u2019 findings in relation to their investigation into tumor organoids. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1535610821003998\" target=\"_blank\" rel=\"noopener\">[2]<\/a> <a href=\"https:\/\/www.issnationallab.org\/release-ax3-life-science-research\/\" target=\"_blank\" rel=\"noopener\">[3]<\/a><\/span><\/p>\n<p class=\"ai-optimize-63\"><span style=\"font-weight: 400;\">By analyzing the growth rates of cancer stem cells, SSCI hope to build on previous Axiom missions and shed light on how cancer develops in order to identify early warning signs.\u00a0<\/span><\/p>\n<p class=\"ai-optimize-64\"><span style=\"font-weight: 400;\">Aboard the same mission, the National Stem Cell Foundation (NSCF) are seeking to utilise 3D brain models to help ascertain key onset markers of neurodegenerative diseases. <a href=\"https:\/\/nationalstemcellfoundation.org\/news\/nscf-travels-with-axiom-space-mission-to-continue-innovative-neurodegeneration-research-on-the-international-space-station\/#:~:text=(January%252018%252C%25202024)%2520\u2013,Center%2520at%2520Cape%2520Canaveral%252C%2520Florida.\" target=\"_blank\" rel=\"noopener\">[4]<\/a><\/span><\/p>\n<p class=\"ai-optimize-65\"><span style=\"font-weight: 400;\">NSCF Researchers hope that by analyzing the effects of microgravity on the 3D models, which are derived from the induced pluripotent stem cells of patients with either Parkinson\u2019s or primary progressive multiple sclerosis, they\u2019ll be able to better understand how these diseases develop.\u00a0\u00a0\u00a0<\/span><\/p>\n<p class=\"ai-optimize-66\"><span style=\"font-weight: 400;\">In this, the third Axiom mission of its kind, researchers hope to take advantage of the different rates at which stem cells develop in space to point out what the future of treatment looks like for some of the most harmful diseases on Earth.<\/span><\/p>\n<p class=\"ai-optimize-67\"><span style=\"font-weight: 400;\">The second significant space mission to launch this month will be on the 29 January.\u00a0<\/span><\/p>\n<p class=\"ai-optimize-68\"><span style=\"font-weight: 400;\">This mission, which has as its main payload materials for the resupply of the International Space Station, will investigate how the absence of gravity plays a role in bone loss. <a href=\"https:\/\/newsnetwork.mayoclinic.org\/discussion\/new-mayo-clinic-stem-cell-research-to-take-flight-into-space\/\" target=\"_blank\" rel=\"noopener\">[5]<\/a><\/span><\/p>\n<p class=\"ai-optimize-69\"><span style=\"font-weight: 400;\">A team from the Mayo Clinic in Florida will analyse the effect of gravity, or lack thereof, on mesenchymal stem cells derived from bone marrow.<\/span><\/p>\n<p class=\"ai-optimize-70\"><span style=\"font-weight: 400;\">Their findings could end up having an impact on the course of clinical trials for a variety of conditions, such as osteoporosis, that take advantage of the powerful regenerative potential of these type of stem cells to regrow bone tissue.<\/span><\/p>\n<p class=\"ai-optimize-71\"><span style=\"font-weight: 400;\">This mission will be the first of two, with the next scheduled tentatively for the end of the year. This second flight should seek to investigate the effect of microgravity on different cell types that similarly occasion either bone formation or loss.<\/span><\/p>\n<p class=\"ai-optimize-72\"><span style=\"font-weight: 400;\">These experiments in space show the truly pioneering research taking place in the field and illustrate the huge potential these incredible cells have for humans on Earth now, and possibly in space in the near future.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p class=\"ai-optimize-73\"><span style=\"font-weight: 400;\">Find out more about what stem cells can do by requesting your FREE Info Kit below.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p class=\"ai-optimize-74\"><strong>Sources<\/strong><\/p>\n<p class=\"ai-optimize-75\"><a href=\"https:\/\/www.axiomspace.com\/missions\/ax3#research\" target=\"_blank\" rel=\"noopener\">[1] <em>Ax-3 Mission Research<\/em>. Axiom Space. https:\/\/www.axiomspace.com\/missions\/ax3#research<\/a><\/p>\n<p class=\"ai-optimize-76\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1535610821003998\" target=\"_blank\" rel=\"noopener\">[2] Vivien Veninga, Emile E. Voest, <em>Tumor organoids: Opportunities and challenges to guide precision medicine<\/em>, Cancer Cell, Volume 39, Issue 9, 2021, Pages 1190-1201, https:\/\/doi.org\/10.1016\/j.ccell.2021.07.020., https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1535610821003998<\/a><\/p>\n<p class=\"ai-optimize-77\"><a href=\"https:\/\/www.issnationallab.org\/release-ax3-life-science-research\/\" target=\"_blank\" rel=\"noopener\">[3] <em>Stem Cell Investigations to Improve Cancer Treatment Among Payloads Flying on Axiom Space\u2019s Third Private Astronaut Mission<\/em>. ISS National Laboratory. 10 January, 2024, https:\/\/www.issnationallab.org\/release-ax3-life-science-research\/<\/a><\/p>\n<p class=\"ai-optimize-78\"><a href=\"https:\/\/www.stemcellsinspace.org\/blog\/2024\/1\/18\/national-stem-cell-foundation-travels-with-axiom-space-mission-to-continue-innovative-neurodegeneration-research-on-the-international-space-station\" target=\"_blank\" rel=\"noopener\">[4] <em>NSCF Travels with Axiom Space Mission to Continue Innovative Neurodegeneration Research on the International Space Station<\/em>. National Stem Cell Foundation. 18 January, 2024, https:\/\/www.stemcellsinspace.org\/blog\/2024\/1\/18\/national-stem-cell-foundation-travels-with-axiom-space-mission-to-continue-innovative-neurodegeneration-research-on-the-international-space-station<\/a><\/p>\n<p class=\"ai-optimize-79\"><a href=\"https:\/\/newsnetwork.mayoclinic.org\/discussion\/new-mayo-clinic-stem-cell-research-to-take-flight-into-space\/\" target=\"_blank\" rel=\"noopener\">[5] <em>New Mayo Clinic stem cell research to take flight into space<\/em>. Mayo Clinic News Network. 18 January, 2024, https:\/\/newsnetwork.mayoclinic.org\/discussion\/new-mayo-clinic-stem-cell-research-to-take-flight-into-space\/<\/a><\/p>\n<p>&nbsp;<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; module_class=&#8221;down-arrow&#8221; _builder_version=&#8221;4.27.4&#8243; background_color=&#8221;#bd144f&#8221; custom_padding=&#8221;0px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;RWP&#8221; module_id=&#8221;request-welcome-pack&#8221; _builder_version=&#8221;4.27.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_layout=&#8221;dark&#8221; use_border_color=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]\n<h3>FIND OUT MORE, REQUEST YOUR FREE INFO KIT TODAY<\/h3>\n<p>All you need to know to make an informed decision.<\/p>\n<p>Provide your contact details to request:<\/p>\n<p>&#8211; Complete Info Kit and your Guide to Cord Blood Banking<br \/>&#8211; Information via email<br \/>&#8211; Contact from our specialist advisors<\/p>\n<p>&nbsp;<\/p>\n\n<div class=\"wpcf7 no-js\" id=\"wpcf7-f14118-o1\" lang=\"en-US\" dir=\"ltr\" data-wpcf7-id=\"14118\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/us\/wp-json\/wp\/v2\/posts\/31738#wpcf7-f14118-o1\" method=\"post\" class=\"wpcf7-form init\" aria-label=\"Contact form\" 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aria-required=\"true\" aria-invalid=\"false\" name=\"delivery_year\"><option value=\"\">Year<\/option><option value=\"2026\">2026<\/option><option value=\"2027\">2027<\/option><\/select><\/span><\/span>\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"primary_address_postalcode\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text c4l-uppercase\" aria-invalid=\"false\" placeholder=\"Zip Code\" value=\"\" type=\"text\" name=\"primary_address_postalcode\" \/><\/span>\n<\/p>\n<p id=\"cf7tosugar_by_post\">By mail?<span class=\"wpcf7-form-control-wrap\" data-name=\"welcome_pack_by_post_c\"><span class=\"wpcf7-form-control wpcf7-checkbox\"><span class=\"wpcf7-list-item first last\"><input type=\"checkbox\" name=\"welcome_pack_by_post_c[]\" value=\"Yes\" \/><span class=\"wpcf7-list-item-label\">Yes<\/span><\/span><\/span><\/span>\n<\/p>\n<p class=\"cf7tosugar_address\"><span class=\"wpcf7-form-control-wrap\" data-name=\"primary_address_street\"><input 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maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text c4l-capitalize\" aria-invalid=\"false\" placeholder=\"Country\" value=\"\" type=\"text\" name=\"primary_address_country\" \/><\/span>\n<\/p>\n<p><input class=\"wpcf7-form-control wpcf7-submit has-spinner wpcf7-button c4l-button-dark gtm-rwp-onpage\" type=\"submit\" value=\"REQUEST\" \/>\n<\/p>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"us\" type=\"hidden\" name=\"webform_site_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"true\" type=\"hidden\" name=\"sugar_crm_lead\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"76dbb9e8-4c86-d341-0772-689602ea5afc\" type=\"hidden\" name=\"campaign_id\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"e4987368-af56-291e-0908-4e82dbf541c4\" type=\"hidden\" name=\"assigned_user_id\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"e4987368-af56-291e-0908-4e82dbf541c4\" type=\"hidden\" name=\"created_by\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"rwp\" type=\"hidden\" name=\"lead_source\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"{EXT_REFERER}\" type=\"hidden\" name=\"webform_referrer_url_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"{COOKIE:_#uid}\" type=\"hidden\" name=\"webform_contact_id_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"request-welcome-pack\" type=\"hidden\" name=\"originating_web_form_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"{IP_ADDRESS}\" type=\"hidden\" name=\"webform_ip_address_c\" \/><input type='hidden' class='wpcf7-pum' value='{\"closepopup\":false,\"closedelay\":0,\"openpopup\":false,\"openpopup_id\":0}' \/><div class=\"wpcf7-response-output\" aria-hidden=\"true\"><\/div>\n<\/form>\n<\/div>\n\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"<p>This month sees two important missions lifting-off into space, both of which will carry out pioneering stem cell research. The first of these has already launched. On 18 January, Ax-3, the third mission by private company Axiom to be launched using Space X rockets, departed for the International Space Station. [1] Aboard were four astronauts [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":31740,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p>Most people know what it\u2019s like to feel sadness. But when feeling down persists for weeks, or even months, it can be a sign of a mental health condition, like depression.<\/p><p>Although today people are well versed and more understanding of depression, some sufferers still find it difficult to find treatments.<\/p><h3>What is depression?<\/h3><p>Depression is a common mental health condition. It is characterised by low mood, feelings of hopelessness, losing interest in things which previously brought a sense of enjoyment, and feeling tearful.<\/p><p>Depression can also manifest in physical ways. Sleeping poorly, feeling tired, experiencing aches, pains, a diminished appetite, and decreased libido can all be impacts of depression. The symptoms range from mild to severe. In mild cases, a persistent low mood may be the cause, while severe cases may result in suicidal feelings or a desire to self harm <a href=\"https:\/\/www.nhs.uk\/mental-health\/conditions\/depression-in-adults\/overview\/\">[1]<\/a>.<\/p><p>Sometimes the causes of depression can be obvious, such as a bereavement or a traumatic event. Other times there might be no known cause, although family history could be the reason. Whatever the reason, once a person has identified they may be depressed, they should go and see their GP.<\/p><h3>What treatments are available?<\/h3><p>There are a plethora of treatments for depression that a doctor can prescribe, from talking therapies to pharmaceutical medications to exercise and more. Sometimes the GP may recommend one treatment or a combination of treatments but they will help support patients and signpost them to services which can bolster their support network.<\/p><p>The good news is that depression is among the most treatable mental health disorders.\u00a0 Between 80% and 90% percent of people with depression eventually respond well to treatment. Almost all patients gain some relief from their symptoms <a href=\"https:\/\/www.psychiatry.org\/patients-families\/depression\/what-is-depression#:~:text=Depression%20is%20among%20the%20most,some%20relief%20from%20their%20symptoms.\">[2]<\/a>.<\/p><h3>Treatment Resistant Depression<\/h3><p>For those with major depressive disorder, however, treatment can be harder to find. With up to one third of adults with the condition failing to respond to treatment, new avenues and treatments are being sought.<\/p><p>\u201cAlthough there is some disagreement as to how to define treatment-resistant depression, a patient is generally considered to have it if the individual hasn\u2019t responded to adequate doses of two different antidepressants taken for a sufficient duration of time, which is usually six weeks,\u201d explains Jaskaran Singh, M.D., Senior Director of Neuroscience, Janssen Pharmaceuticals <a href=\"https:\/\/www.jnj.com\/health-and-wellness\/4-facts-about-treatment-resistant-depression\">[3]<\/a>.<\/p><p>The theory that depression may have causes currently unknown by scientists is one theory researchers are exploring to try and combat resistance to treatment.<\/p><p>\u201cOne of the more modern theories is that depression creates inflammation in the brain, or that inflammation in the brain creates depression. Traditional antidepressants only affect neurotransmitters, so this may be why some patients don\u2019t respond to them.\u201d\u00a0 says Alexander Papp, M.D., a psychiatrist at UC San Diego Health <a href=\"https:\/\/www.jnj.com\/health-and-wellness\/4-facts-about-treatment-resistant-depression\">[4]<\/a>.<\/p><p>Whether or not this is the case, researchers are still trying to find solutions to Treatment Resistant Depression.<\/p><h3>The Potential of Cord Blood Therapy<\/h3><p>One study using umbilical cord blood cells delivered promising results. The study administered concentrated umbilical cord blood cells at a dose of 250 million cells via weekly injections over 4 weeks with 1 week intervals, to women who suffered with Treatment Resistant Depression.\u00a0 The results were tested against a control group who received a placebo.<\/p><p>The study found that the therapeutic potential of umbilical cord blood cell concentrate can be used to overcome treatment resistance formed in depressive patients <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7087609\/\">[5]<\/a>. Other studies have also found that cellular therapies may have a role in combating Treatment Resistant Depression <a href=\"https:\/\/www.mdpi.com\/1999-4923\/15\/3\/814\">[6]<\/a> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8474995\/\">[7]<\/a>.<\/p><p>These studies give hope for finding new treatments. With the help of umbilical cord blood cells, those suffering from Treatment Resistant Depression may one day find relief from the debilitating illness affecting their day to day lives.<\/p><p>If you think you may be suffering from depression please speak to your GP.<\/p><p>\u00a0<\/p><p><strong>Organisations who can help if you need someone to talk to:<\/strong><\/p><p><strong>Samaritans: Call 116 123 - It\u2019s FREE and available 24\/7<\/strong><\/p><p><strong>Shout 85258: text SHOUT to 85258 - It\u2019s FREE and available 24\/7<\/strong><\/p><p><strong>CALM: Call 0800 58 58 58 or use their webchat <a href=\"https:\/\/www.thecalmzone.net\/get-support#open-calmbot\">here<\/a>.\u00a0 The helpline and webchat are both open 5pm to midnight, 365 days a year.<\/strong><\/p><p>\u00a0<\/p>","_et_gb_content_width":"","_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[55,87,9280],"tags":[9252,9288,9248,9261],"class_list":["post-31738","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","category-stem-cell-news","category-stem-cell-therapies","tag-blog","tag-hair-loss","tag-stem-cell-therapy","tag-trial"],"_links":{"self":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/31738","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/comments?post=31738"}],"version-history":[{"count":10,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/31738\/revisions"}],"predecessor-version":[{"id":38773,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/31738\/revisions\/38773"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/media\/31740"}],"wp:attachment":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/media?parent=31738"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/categories?post=31738"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/tags?post=31738"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}