{"id":32614,"date":"2024-05-07T14:49:21","date_gmt":"2024-05-07T14:49:21","guid":{"rendered":"https:\/\/cells4life.com\/?p=32614"},"modified":"2025-10-29T16:02:45","modified_gmt":"2025-10-29T16:02:45","slug":"stem-cells-shown-to-aid-repair-after-cardiac-arrest","status":"publish","type":"post","link":"https:\/\/cells4life.com\/us\/2024\/05\/stem-cells-shown-to-aid-repair-after-cardiac-arrest\/","title":{"rendered":"Stem Cells Shown to Aid Repair After Cardiac Arrest"},"content":{"rendered":"[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]\n<p class=\"ai-optimize-31\"><span style=\"font-weight: 400;\">In a study first published in April\u2019s edition of <\/span><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/adfm.202309866\" target=\"_blank\" rel=\"noopener\"><i><span style=\"font-weight: 400;\">Advanced Functional Materials<\/span><\/i><\/a><span style=\"font-weight: 400;\">, researchers found that stem cells boost natural repair following cardiac arrest.<\/span><\/p>\n<p class=\"ai-optimize-32\"><span style=\"font-weight: 400;\">The most common consequence of cardiac arrest is brain injury. Decreased blood flow and oxygen to the brain can result in damage to specific areas such as the temporal lobe, which is responsible for memories. <\/span><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/heart-attack-brain-damage#treatment\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">[1]<\/span><\/a><\/p>\n<p class=\"ai-optimize-33\"><span style=\"font-weight: 400;\">According to <a href=\"https:\/\/theheartfoundation.org\/cpr-basics-four-steps-to-save-a-life\/\" target=\"_blank\" rel=\"noopener\">The Heart Foundation<\/a>, more than 350,000 out-of-hospital cardiac arrests occur in the U.S. each year, with only around 40% receiving immediate help, even though CPR can double or triple survival chances.<\/span><\/p>\n<p class=\"ai-optimize-34\"><span style=\"font-weight: 400;\">While there are currently steps towards improving these survival rates &#8211; mainly public awareness and educational campaigns focused on immediate response <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10776426\/#:~:text=The%20most%20important%20step%20in,with%20increased%20survival%20after%20OHCA.&amp;text=Increasing%20the%20lay%20resuscitation%20rate,a%20threefold%20increase%20in%20survival.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">[2]<\/span><\/a><span style=\"font-weight: 400;\"> &#8211; better survival rates potentially means more patients suffering from brain injury, which can range in severity.<\/span><\/p>\n<p class=\"ai-optimize-35\"><span style=\"font-weight: 400;\">What researchers at the University of Maryland School of Medicine in the U.S. have found is that neural stem cells can help with repairing post-cardiac arrest brain damage when their carbohydrate structure is manipulated. <\/span><a href=\"https:\/\/www.umaryland.edu\/news\/archived-news\/may-2024\/stem-cell-therapy-boosts-natural-repair-after-cardiac-arrest.php\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">[3]<\/span><\/a><\/p>\n<p class=\"ai-optimize-36\"><span style=\"font-weight: 400;\">In an animal study using rats, scientists applied sugar molecules to the neural stem cells in a process called glycoengineering.\u00a0<\/span><\/p>\n<p class=\"ai-optimize-37\"><span style=\"font-weight: 400;\">It\u2019s thought that the application of these sugar molecules provide the neural stem cells with a better chance of retention and integration within the harsh microenvironment of the brain.<\/span><\/p>\n<p class=\"ai-optimize-38\"><span style=\"font-weight: 400;\">Researchers examined the efficacy of the \u2018sugar-coated\u2019 neural stem cells that had been pretreated with TProp (the name of the modified sugar molecule applied) with naive human neural stem cells.<\/span><\/p>\n<p class=\"ai-optimize-39\"><span style=\"font-weight: 400;\">They found through subsequent testing that the stem cells that had been pretreated with TProp improved brain function substantially, along with reducing anxiety and depression-related behaviors.\u00a0\u00a0<\/span><\/p>\n<p class=\"ai-optimize-40\"><span style=\"font-weight: 400;\">The ability for synapses to modify the strength of their connections (otherwise known as synapse plasticity) also improved, with the TProp group also demonstrating a reduction in neuroinflammation in the central nervous system.<\/span><\/p>\n<p class=\"ai-optimize-41\"><span style=\"font-weight: 400;\">Overall, the findings from the University of Maryland are promising as they indicate that these glycoengineered stem cells could help regenerate connections between synapses in the brain that have been affected by cardiac arrest related injury in humans.<\/span><\/p>\n<p class=\"ai-optimize-42\"><span style=\"font-weight: 400;\">The next steps will involve tests on larger animals before hopefully moving to a clinical study.<\/span><\/p>\n<p class=\"ai-optimize-43\"><span style=\"font-weight: 400;\">If you want to know more about how you can save your baby\u2019s powerful stem cells, fill out the form below for your free info kit.\u00a0<\/span><\/p>\n<p class=\"ai-optimize-44\"><b>References<\/b><\/p>\n<p class=\"ai-optimize-45\"><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/heart-attack-brain-damage#effects\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">[1] (2023, July 7). <\/span><i><span style=\"font-weight: 400;\">Can a heart attack cause brain damage?<\/span><\/i><span style=\"font-weight: 400;\"> Medical News Today. https:\/\/www.medicalnewstoday.com\/articles\/heart-attack-brain-damage#effects<\/span><\/a><\/p>\n<p class=\"ai-optimize-46\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10776426\/#:~:text=The%20most%20important%20step%20in,with%20increased%20survival%20after%20OHCA.&amp;text=Increasing%20the%20lay%20resuscitation%20rate,a%20threefold%20increase%20in%20survival.\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">[2] Horriar, Lina et al. \u201cImproving survival after cardiac arrest in Europe: The synergetic effect of rescue chain strategies.\u201d Resuscitation plus vol. 17 100533. 21 Dec. 2023, doi:10.1016\/j.resplu.2023.100533<\/span><\/a><\/p>\n<p class=\"ai-optimize-47\"><a href=\"https:\/\/www.umaryland.edu\/news\/archived-news\/may-2024\/stem-cell-therapy-boosts-natural-repair-after-cardiac-arrest.php\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">[3] (2024, May 9). <\/span><i><span style=\"font-weight: 400;\">Stem Cell Therapy Boosts Natural Repair After Cardiac Arrest<\/span><\/i><span style=\"font-weight: 400;\">. University of Maryland Baltimore. https:\/\/www.umaryland.edu\/news\/archived-news\/may-2024\/stem-cell-therapy-boosts-natural-repair-after-cardiac-arrest.php<\/span><\/a><\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; module_class=&#8221;down-arrow&#8221; _builder_version=&#8221;4.27.4&#8243; background_color=&#8221;#bd144f&#8221; custom_padding=&#8221;0px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;RWP&#8221; module_id=&#8221;request-welcome-pack&#8221; _builder_version=&#8221;4.27.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; background_layout=&#8221;dark&#8221; use_border_color=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]\n<h3>FIND OUT MORE, REQUEST YOUR FREE INFO KIT TODAY<\/h3>\n<p>All you need to know to make an informed decision.<\/p>\n<p>Provide your contact details to request:<\/p>\n<p>&#8211; Complete Info Kit and your Guide to Cord Blood Banking<br \/>&#8211; Information via email<br \/>&#8211; Contact from our specialist advisors<\/p>\n<p>&nbsp;<\/p>\n\n<div class=\"wpcf7 no-js\" id=\"wpcf7-f14118-o1\" lang=\"en-US\" dir=\"ltr\" data-wpcf7-id=\"14118\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/us\/wp-json\/wp\/v2\/posts\/32614#wpcf7-f14118-o1\" method=\"post\" class=\"wpcf7-form init\" aria-label=\"Contact form\" novalidate=\"novalidate\" data-status=\"init\">\n<fieldset class=\"hidden-fields-container\"><input type=\"hidden\" name=\"_wpcf7\" value=\"14118\" \/><input type=\"hidden\" name=\"_wpcf7_version\" value=\"6.1.5\" \/><input type=\"hidden\" name=\"_wpcf7_locale\" value=\"en_US\" \/><input type=\"hidden\" name=\"_wpcf7_unit_tag\" value=\"wpcf7-f14118-o1\" \/><input type=\"hidden\" name=\"_wpcf7_container_post\" value=\"0\" \/><input type=\"hidden\" name=\"_wpcf7_posted_data_hash\" value=\"\" \/>\n<\/fieldset>\n<p>Title* <span class=\"wpcf7-form-control-wrap\" data-name=\"salutation\"><select class=\"wpcf7-form-control wpcf7-select wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" name=\"salutation\"><option value=\"- Select -\">- Select -<\/option><option value=\"Mr\">Mr<\/option><option value=\"Mrs\">Mrs<\/option><option value=\"Miss\">Miss<\/option><option value=\"Ms\">Ms<\/option><option value=\"Dr\">Dr<\/option><option value=\"Prof\">Prof<\/option><option value=\"Sir\">Sir<\/option><option value=\"Madam\">Madam<\/option><option value=\"Other\">Other<\/option><\/select><\/span>\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"first_name\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required c4l-capitalize\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"First Name(s)*\" value=\"\" type=\"text\" name=\"first_name\" \/><\/span>\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"last_name\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required c4l-capitalize\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"Last Name*\" value=\"\" type=\"text\" name=\"last_name\" \/><\/span>\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"email1\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-email wpcf7-validates-as-required wpcf7-text wpcf7-validates-as-email email1_3838\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"Email Address*\" value=\"\" type=\"email\" name=\"email1\" \/><\/span>\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"email_hp\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-email wpcf7-text wpcf7-validates-as-email c4l-hp\" aria-invalid=\"false\" placeholder=\"Alternate Email Address\" value=\"\" type=\"email\" name=\"email_hp\" \/><\/span>\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"phone_mobile\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"Phone Number*\" value=\"\" type=\"text\" name=\"phone_mobile\" \/><\/span>\n<\/p>\n<p>Due Date* <span class=\"date-row-cf7-custom\"><span class=\"wpcf7-form-control-wrap\" data-name=\"delivery_month\"><select class=\"wpcf7-form-control wpcf7-select wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" name=\"delivery_month\"><option value=\"\">Month<\/option><option value=\"01\">Jan<\/option><option value=\"02\">Feb<\/option><option value=\"03\">Mar<\/option><option value=\"04\">Apr<\/option><option value=\"05\">May<\/option><option value=\"06\">Jun<\/option><option value=\"07\">Jul<\/option><option value=\"08\">Aug<\/option><option value=\"09\">Sep<\/option><option value=\"10\">Oct<\/option><option value=\"11\">Nov<\/option><option value=\"12\">Dec<\/option><\/select><\/span><span class=\"wpcf7-form-control-wrap\" data-name=\"delivery_day\"><select class=\"wpcf7-form-control wpcf7-select wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" name=\"delivery_day\"><option value=\"\">Day<\/option><option value=\"01\">01<\/option><option value=\"02\">02<\/option><option value=\"03\">03<\/option><option value=\"04\">04<\/option><option value=\"05\">05<\/option><option value=\"06\">06<\/option><option value=\"07\">07<\/option><option value=\"08\">08<\/option><option value=\"09\">09<\/option><option value=\"10\">10<\/option><option value=\"11\">11<\/option><option value=\"12\">12<\/option><option value=\"13\">13<\/option><option value=\"14\">14<\/option><option value=\"15\">15<\/option><option value=\"16\">16<\/option><option value=\"17\">17<\/option><option value=\"18\">18<\/option><option value=\"19\">19<\/option><option value=\"20\">20<\/option><option value=\"21\">21<\/option><option value=\"22\">22<\/option><option value=\"23\">23<\/option><option value=\"24\">24<\/option><option value=\"25\">25<\/option><option value=\"26\">26<\/option><option value=\"27\">27<\/option><option value=\"28\">28<\/option><option value=\"29\">29<\/option><option value=\"30\">30<\/option><option value=\"31\">31<\/option><\/select><\/span><span class=\"wpcf7-form-control-wrap\" data-name=\"delivery_year\"><select class=\"wpcf7-form-control wpcf7-select wpcf7-validates-as-required\" aria-required=\"true\" aria-invalid=\"false\" name=\"delivery_year\"><option value=\"\">Year<\/option><option value=\"2026\">2026<\/option><option value=\"2027\">2027<\/option><\/select><\/span><\/span>\n<\/p>\n<p><span class=\"wpcf7-form-control-wrap\" data-name=\"primary_address_postalcode\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text c4l-uppercase\" aria-invalid=\"false\" placeholder=\"Zip Code\" value=\"\" type=\"text\" name=\"primary_address_postalcode\" \/><\/span>\n<\/p>\n<p id=\"cf7tosugar_by_post\">By mail?<span class=\"wpcf7-form-control-wrap\" data-name=\"welcome_pack_by_post_c\"><span class=\"wpcf7-form-control wpcf7-checkbox\"><span class=\"wpcf7-list-item first last\"><input type=\"checkbox\" name=\"welcome_pack_by_post_c[]\" value=\"Yes\" \/><span class=\"wpcf7-list-item-label\">Yes<\/span><\/span><\/span><\/span>\n<\/p>\n<p class=\"cf7tosugar_address\"><span class=\"wpcf7-form-control-wrap\" data-name=\"primary_address_street\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text c4l-capitalize\" aria-invalid=\"false\" placeholder=\"Address 1\" value=\"\" type=\"text\" name=\"primary_address_street\" \/><\/span>\n<\/p>\n<p class=\"cf7tosugar_address\"><span class=\"wpcf7-form-control-wrap\" data-name=\"primary_address_city\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text c4l-capitalize\" aria-invalid=\"false\" placeholder=\"Address 2\" value=\"\" type=\"text\" name=\"primary_address_city\" \/><\/span>\n<\/p>\n<p class=\"cf7tosugar_address\"><span class=\"wpcf7-form-control-wrap\" data-name=\"primary_address_state\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text c4l-capitalize\" aria-invalid=\"false\" placeholder=\"State\" value=\"\" type=\"text\" name=\"primary_address_state\" \/><\/span>\n<\/p>\n<p class=\"cf7tosugar_address\"><span class=\"wpcf7-form-control-wrap\" data-name=\"primary_address_country\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text c4l-capitalize\" aria-invalid=\"false\" placeholder=\"Country\" value=\"\" type=\"text\" name=\"primary_address_country\" \/><\/span>\n<\/p>\n<p><input class=\"wpcf7-form-control wpcf7-submit has-spinner wpcf7-button c4l-button-dark gtm-rwp-onpage\" type=\"submit\" value=\"REQUEST\" \/>\n<\/p>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"us\" type=\"hidden\" name=\"webform_site_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"true\" type=\"hidden\" name=\"sugar_crm_lead\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"76dbb9e8-4c86-d341-0772-689602ea5afc\" type=\"hidden\" name=\"campaign_id\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"e4987368-af56-291e-0908-4e82dbf541c4\" type=\"hidden\" name=\"assigned_user_id\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"e4987368-af56-291e-0908-4e82dbf541c4\" type=\"hidden\" name=\"created_by\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"rwp\" type=\"hidden\" name=\"lead_source\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"{EXT_REFERER}\" type=\"hidden\" name=\"webform_referrer_url_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"{COOKIE:_#uid}\" type=\"hidden\" name=\"webform_contact_id_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"request-welcome-pack\" type=\"hidden\" name=\"originating_web_form_c\" \/>\n<input class=\"wpcf7-form-control wpcf7-hidden\" value=\"{IP_ADDRESS}\" type=\"hidden\" name=\"webform_ip_address_c\" \/><input type='hidden' class='wpcf7-pum' value='{\"closepopup\":false,\"closedelay\":0,\"openpopup\":false,\"openpopup_id\":0}' \/><div class=\"wpcf7-response-output\" aria-hidden=\"true\"><\/div>\n<\/form>\n<\/div>\n\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"<p>In a study first published in April\u2019s edition of Advanced Functional Materials, researchers found that stem cells boost natural repair following cardiac arrest. The most common consequence of cardiac arrest is brain injury. Decreased blood flow and oxygen to the brain can result in damage to specific areas such as the temporal lobe, which is [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":32616,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p>Most people know what it\u2019s like to feel sadness. But when feeling down persists for weeks, or even months, it can be a sign of a mental health condition, like depression.<\/p><p>Although today people are well versed and more understanding of depression, some sufferers still find it difficult to find treatments.<\/p><h3>What is depression?<\/h3><p>Depression is a common mental health condition. It is characterised by low mood, feelings of hopelessness, losing interest in things which previously brought a sense of enjoyment, and feeling tearful.<\/p><p>Depression can also manifest in physical ways. Sleeping poorly, feeling tired, experiencing aches, pains, a diminished appetite, and decreased libido can all be impacts of depression. The symptoms range from mild to severe. In mild cases, a persistent low mood may be the cause, while severe cases may result in suicidal feelings or a desire to self harm <a href=\"https:\/\/www.nhs.uk\/mental-health\/conditions\/depression-in-adults\/overview\/\">[1]<\/a>.<\/p><p>Sometimes the causes of depression can be obvious, such as a bereavement or a traumatic event. Other times there might be no known cause, although family history could be the reason. Whatever the reason, once a person has identified they may be depressed, they should go and see their GP.<\/p><h3>What treatments are available?<\/h3><p>There are a plethora of treatments for depression that a doctor can prescribe, from talking therapies to pharmaceutical medications to exercise and more. Sometimes the GP may recommend one treatment or a combination of treatments but they will help support patients and signpost them to services which can bolster their support network.<\/p><p>The good news is that depression is among the most treatable mental health disorders.\u00a0 Between 80% and 90% percent of people with depression eventually respond well to treatment. Almost all patients gain some relief from their symptoms <a href=\"https:\/\/www.psychiatry.org\/patients-families\/depression\/what-is-depression#:~:text=Depression%20is%20among%20the%20most,some%20relief%20from%20their%20symptoms.\">[2]<\/a>.<\/p><h3>Treatment Resistant Depression<\/h3><p>For those with major depressive disorder, however, treatment can be harder to find. With up to one third of adults with the condition failing to respond to treatment, new avenues and treatments are being sought.<\/p><p>\u201cAlthough there is some disagreement as to how to define treatment-resistant depression, a patient is generally considered to have it if the individual hasn\u2019t responded to adequate doses of two different antidepressants taken for a sufficient duration of time, which is usually six weeks,\u201d explains Jaskaran Singh, M.D., Senior Director of Neuroscience, Janssen Pharmaceuticals <a href=\"https:\/\/www.jnj.com\/health-and-wellness\/4-facts-about-treatment-resistant-depression\">[3]<\/a>.<\/p><p>The theory that depression may have causes currently unknown by scientists is one theory researchers are exploring to try and combat resistance to treatment.<\/p><p>\u201cOne of the more modern theories is that depression creates inflammation in the brain, or that inflammation in the brain creates depression. Traditional antidepressants only affect neurotransmitters, so this may be why some patients don\u2019t respond to them.\u201d\u00a0 says Alexander Papp, M.D., a psychiatrist at UC San Diego Health <a href=\"https:\/\/www.jnj.com\/health-and-wellness\/4-facts-about-treatment-resistant-depression\">[4]<\/a>.<\/p><p>Whether or not this is the case, researchers are still trying to find solutions to Treatment Resistant Depression.<\/p><h3>The Potential of Cord Blood Therapy<\/h3><p>One study using umbilical cord blood cells delivered promising results. The study administered concentrated umbilical cord blood cells at a dose of 250 million cells via weekly injections over 4 weeks with 1 week intervals, to women who suffered with Treatment Resistant Depression.\u00a0 The results were tested against a control group who received a placebo.<\/p><p>The study found that the therapeutic potential of umbilical cord blood cell concentrate can be used to overcome treatment resistance formed in depressive patients <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7087609\/\">[5]<\/a>. Other studies have also found that cellular therapies may have a role in combating Treatment Resistant Depression <a href=\"https:\/\/www.mdpi.com\/1999-4923\/15\/3\/814\">[6]<\/a> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8474995\/\">[7]<\/a>.<\/p><p>These studies give hope for finding new treatments. With the help of umbilical cord blood cells, those suffering from Treatment Resistant Depression may one day find relief from the debilitating illness affecting their day to day lives.<\/p><p>If you think you may be suffering from depression please speak to your GP.<\/p><p>\u00a0<\/p><p><strong>Organisations who can help if you need someone to talk to:<\/strong><\/p><p><strong>Samaritans: Call 116 123 - It\u2019s FREE and available 24\/7<\/strong><\/p><p><strong>Shout 85258: text SHOUT to 85258 - It\u2019s FREE and available 24\/7<\/strong><\/p><p><strong>CALM: Call 0800 58 58 58 or use their webchat <a href=\"https:\/\/www.thecalmzone.net\/get-support#open-calmbot\">here<\/a>.\u00a0 The helpline and webchat are both open 5pm to midnight, 365 days a year.<\/strong><\/p><p>\u00a0<\/p>","_et_gb_content_width":"","_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[55,9285,60,87,9280],"tags":[9252,9248,9261],"class_list":["post-32614","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","category-heart-and-vascular-disease","category-news","category-stem-cell-news","category-stem-cell-therapies","tag-blog","tag-stem-cell-therapy","tag-trial"],"_links":{"self":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/32614","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/comments?post=32614"}],"version-history":[{"count":10,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/32614\/revisions"}],"predecessor-version":[{"id":38720,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/posts\/32614\/revisions\/38720"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/media\/32616"}],"wp:attachment":[{"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/media?parent=32614"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/categories?post=32614"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cells4life.com\/us\/wp-json\/wp\/v2\/tags?post=32614"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}