Down\u2019s syndrome is a genetic disorder caused by an abnormality, involving chromosome 21. The condition results in impaired cognitive development and a distinctive physical appearance. Scientists don\u2019t yet truly understand the underlying cause of Down\u2019s syndrome and in 94% of cases it likely simply to have been a fluke of nature.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row background_position=”top_left” background_repeat=”repeat” background_size=”initial”][et_pb_column type=”1_3″][et_pb_blurb url_new_window=”off” use_icon=”off” icon_color=”#00abc9″ use_circle=”off” circle_color=”#00abc9″ use_circle_border=”off” circle_border_color=”#00abc9″ image=”https:\/\/cells4life.com\/us\/wp-content\/uploads\/2016\/11\/2aday.jpg” alt=”2 babies are born with Down’s syndrome every day in the UK” icon_placement=”top” animation=”top” background_layout=”light” text_orientation=”center” use_icon_font_size=”off” use_border_color=”off” border_color=”#ffffff” border_style=”solid” background_position=”top_left” background_repeat=”repeat” background_size=”initial” image_max_width=”100%”]\n
In the UK, 2 babies are born with Down’s syndrome every day.<\/span><\/p>\n[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_3″][et_pb_blurb url_new_window=”off” use_icon=”off” icon_color=”#00abc9″ use_circle=”off” circle_color=”#00abc9″ use_circle_border=”off” circle_border_color=”#00abc9″ image=”https:\/\/cells4life.com\/us\/wp-content\/uploads\/2016\/11\/60000uk.jpg” alt=”60,000 people in the UK have Down’s syndrome” icon_placement=”top” animation=”top” background_layout=”light” text_orientation=”center” use_icon_font_size=”off” use_border_color=”off” border_color=”#ffffff” border_style=”solid” background_position=”top_left” background_repeat=”repeat” background_size=”initial” image_max_width=”100%”]\n There are currently 60,000 people in Britain with the condition.<\/span><\/p>\n[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_3″][et_pb_blurb url_new_window=”off” use_icon=”off” icon_color=”#00abc9″ use_circle=”off” circle_color=”#00abc9″ use_circle_border=”off” circle_border_color=”#00abc9″ image=”https:\/\/cells4life.com\/us\/wp-content\/uploads\/2016\/11\/3tests.jpg” alt=”Test for Down’s syndrome” icon_placement=”top” animation=”top” background_layout=”light” text_orientation=”center” use_icon_font_size=”off” use_border_color=”off” border_color=”#ffffff” border_style=”solid” background_position=”top_left” background_repeat=”repeat” background_size=”initial” image_max_width=”100%”]\n There are 3 types of test for Down\u2019s syndrome.<\/span><\/p>\n[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row background_position=”top_left” background_repeat=”repeat” background_size=”initial”][et_pb_column type=”4_4″][et_pb_text background_layout=”light” text_orientation=”left” use_border_color=”off” border_color=”#ffffff” border_style=”solid” background_position=”top_left” background_repeat=”repeat” background_size=”initial”]\n Currently there are three main types of test available and they can be broken down into two categories: screening and diagnostic testing. The Combined Test and NIPT are screenings and indicate the risk of a baby having Down\u2019s syndrome, whereas Amniocentesis and CVS provide a definitive diagnosis.<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row background_position=”top_left” background_repeat=”repeat” background_size=”initial”][et_pb_column type=”4_4″][et_pb_text background_layout=”light” text_orientation=”left” use_border_color=”off” border_color=”#ffffff” border_style=”solid” background_position=”top_left” background_repeat=”repeat” background_size=”initial”]\n Combined Test<\/span> Non-Invasive Prenatal Testing (NIPT)<\/span> Chorion Villus Sampling (CVS)\/ Amniocentesis<\/span> There are a variety of NIPT services available that test for Down\u2019s syndrome and much more. These include Panaroma, Harmony, NIFTY and Genesis Serenity<\/p>\n Cells4Life offer the Panoroma test as it is the most accurate Down\u2019s Syndrome screening available, with a detection rate of >99%. It is also screens for several conditions that other tests do not, including triploidy, molar pregnancy and vanishing twin, and is the only test to differentiate between maternal and fetal DNA, resulting in a significant reduction is false positives.<\/p>\n The Panorama screens for the following conditions:<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row make_fullwidth=”off” use_custom_width=”off” width_unit=”on” use_custom_gutter=”off” padding_mobile=”off” allow_player_pause=”off” parallax=”off” parallax_method=”off” make_equal=”off” parallax_1=”off” parallax_method_1=”off” parallax_2=”off” parallax_method_2=”off” parallax_3=”off” parallax_method_3=”off” column_padding_mobile=”on” background_position=”top_left” background_repeat=”repeat” background_size=”initial”][et_pb_column type=”1_3″][et_pb_image src=”https:\/\/cells4life.com\/us\/wp-content\/uploads\/2016\/02\/chromo1.jpg” title_text=”Chromosome Test” show_in_lightbox=”off” url_new_window=”off” animation=”top” sticky=”off” align=”center” force_fullwidth=”off” always_center_on_mobile=”on” use_border_color=”off” border_color=”#ffffff” border_style=”solid” animation_style=”slide” animation_duration=”500ms” animation_intensity_slide=”10%” animation_direction=”top” show_bottom_space=”on”]\n[\/et_pb_image][et_pb_text admin_label=”Chromosome Abnormalities” background_layout=”light” text_orientation=”left” text_font_size=”14″ use_border_color=”off” border_color=”#ffffff” border_style=”solid” background_position=”top_left” background_repeat=”repeat” background_size=”initial”]\n Learn more about non-invasive prenatal testing<\/a> and our test for down’s syndrome on on our information pages.<\/p>\n References<\/span><\/p>\n Find out more about cord blood banking by downloading a Welcome Pack now.<\/p>\n\n <\/p> How can I test for Down\u2019s syndrome?<\/h2>\n
\nThis test is available to all expectant mothers from 10-14 weeks of pregnancy and gives a result based on a combination of the mother\u2019s age, an ultrasound scan, and a blood test. The Combined Test has a detection rate of 90%, however, 1 in 20 positive results will be false. This means 5% of parents are left worrying without reason and may evening undergo the far riskier Amniocentesis or CVS tests unnecessarily as a result.<\/p>\n
\nThis newer kind of test is not yet available on the NHS, however, it can be requested through private clinics. It involves a simple blood test that analyses cell free DNA found in the mother\u2019s plasma. NIPT offers a detection rate of >98% and up to a 0.01% false positive rate, making it far more accurate than the Combined Test.<\/p>\n
\nThese invasive tests follow a positive Combined Test or non\u2013invasive screening and involve passing a fine needle through the mother\u2019s abdomen to collected a sample of cells from either the placenta or surrounding fluid. Whilst both tests deliver an accurate diagnosis of the condition they are not without risk – the procedure carries a 1% chance of causing miscarriage.<\/p>\n[\/et_pb_text][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=FvFewgWIKJg”]\n[\/et_pb_video][\/et_pb_column][\/et_pb_row][et_pb_row background_position=”top_left” background_repeat=”repeat” background_size=”initial”][et_pb_column type=”4_4″][et_pb_text background_layout=”light” text_orientation=”left” use_border_color=”off” border_color=”#ffffff” border_style=”solid” background_position=”top_left” background_repeat=”repeat” background_size=”initial”]\nNon-invasive prenatal testing with Cells4Life<\/h2>\n
Chromosome Abnormalities:<\/h3>\n
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Sex Chromosome Abnormalities:<\/h3>\n
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Microdeletions:<\/h3>\n
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Request a Welcome Pack<\/h2>\n
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